Research and innovation (R&I) feature high in both the African Union’s and the European Union’s agenda. While the African Union “Science, Technology and Innovation Strategy for Africa 2024” (STISA-2024) places science, technology and innovation at the epicentre of Africa’s socio-economic development and growth, European investments in R&I are seen as a means to help Europe to compete globally and improve the daily lives of people.Under the AU-EU partnership, both continents have also confirmed their commitment to strengthen R&I collaboration and partnership to address common or complementary society challenges. The EU’s main tool to support such collaborative efforts is the Horizon Europe Framework programme which will run over the period 2021-2027. This programme, which builds on the previous R&I framework programmes, also integrates new instruments such as “missions” and “European partnerships” which aim at finding new R&I research funding instruments and innovative ways of collaboration involving all stakeholders (from consumers to industry) as partners. In this context, it will be important to understand how new joint research and innovation (R&I) mechanisms can support research and development activities.Through an online survey, African and European partners were invited to share their experience with LEAPAgri and the lessons learned in order to develop suggestions for a strategy that would promote the partnership forward by evaluating and identifying mechanisms to sustain collaboration and innovation in the FNSSA field. All 24 partners of the LEAP-Agri consortium were asked to share their opinion which is highly valuable since,apart from being partners in the project, most of them also represent national agencies or funding bodies with solid experience in financing FNSSA's R&I activities. The participants shared their own experience in the field, either through LEAP-Agri